Quartz Crystal Microbalance Study of Dna Immobilization and Hybridization for Dna Sensor Development
نویسندگان
چکیده
Piezoelectric materials such as quartz can be used to detect mass change due to their piezoelectric properties. Quartz Crystal Microbalance (QCM) is an extremely sensitive mass sen frequency biosensor mass mea for QCM DNA biosensor was developed. The potential for QCM to be employed as immunosensor sor, capable of measuring sub-nanogram levels by detecting change in the of a quartz crystal resonator, which makes it a promising candidate for applications. In this project, the mechanistic theories related to QCM mass measurement was reviewed and summarized. Based on the theories, a lab-scale QCM surement unit was set up. Fundamental theories and experimental techniques DNA detection were investigated, and a protocol for the construction of QCM
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